Major sperm protein


The major sperm protein (MSP) is a nematode specific small protein of amino acids with a molecular weight of 14 kDa. It is the key player in the motility.

Major sperm protein as a diagnostic antigen for onchocerciasis. - PubMed - NCBI

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Meiotic arrest and oocyte maturation

Nematode sperm are unusual amoeboid cells in which motility is not based on actin, but instead on the major sperm protein (MSP). MSP is a dimeric molecule.

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Major sperm protein
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Role of major sperm protein (MSP) in the protrusion and retraction of Ascaris sperm.

Description:Description Nematode sperm are unusual amoeboid cells in which motility is not based on actin, but instead on the major sperm protein MSP. MSP is a dimeric molecule that polymerises to form non-polar filaments constructed from two helical subfilaments that wind round one another. The filaments then assemble into larger macromolecular assemblies called fibre complexes. An about amino acid domain similar to MSP has been found in other proteins, including: VAP33 is required for neurotransmitter release.

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Views: 9583 Date: 2018-09-01 Favorited: 27 favorites

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